Chromosome 21

A veteran high school teacher befriends a younger art teacher, who is having an affair with one of her 15-year-old students. However, her intentions with this new "friend" also go well beyond platonic friendship.

Bernice "Bernie" Rhodenbarr is a burglar by trade, and she runs a bookstore as well. Her friend Carl Hefler is a dog groomer. After a successful burglary, it's discovered that a dead body was in the house she burgled. As she's the only one who can be placed at the scene of the crime, she has to use her criminal skills to clear her name of the murder AND avoid getting charged with the burglary.

A young man with Down's Syndrome romantically pursues a small town single mom who is still mixed up with her volatile ex-boyfriend.

A young Los Angeles police officer and a mysterious gnome become unlikely partners as they track a killer. When a sting operation goes awry, officer Casey is blamed for the murder of his colleague and Gnorm the gnome is the only witness.

An undercover officer tracks waterfront corruption from California to New Orleans and back.

Luke, an independent young man with Down's syndrome stumbles upon a wild and life changing friendship.

A man known to be a mute is suspected of committing a murder, as he was noticed at the scene. However, witnesses saw and heard him talking as he was leaving the scene of the crime. The police must determine if he is the actual killer or if he is being framed.

Calvin Campbell is a former professional baseball player sent to an early retirement due to his panic attacks at the plate. Even though he had all the talent for the big leagues, he struggles with the curveballs life has thrown him. Today, he mindlessly sleepwalks through his days and the challenge of raising his teenager daughter. His life is in a slow downward spiral when it is suddenly awakened and invigorated by the most unlikely person – Produce, a young-man with Down syndrome who works at the local grocery store.

A man having marital problems with his shrewish wife picks up a young, pretty and pregnant hitchhiker. Before he knows it, he's in over his head and mixed up in violence and murder.

The Senior Prank is family drama about a group of popular teenagers who wage a fake campaign to elect a girl with Down Syndrome as the schools Homecoming Queen. Inspired by real bullying events witnessed by real teenagers in their local high schools.

A beautiful showgirl, name "the Canary" is a scheming nightclub singer. Blackmailing is her game and with that she ends up dead. But who killed "the Canary". All the suspects knew and were used by her and everyone had a motive to see her dead. The only witness to the crime has also been 'rubbed out'. Only one man, the keen, fascinating, debonair detective Philo Vance, would be able to figure out who is the killer. Written by Tony Fontana

Homophobic detective Mark Rima must "partner" up with the very gay and flamboyant Detective Chris Riant to stop a serial killing Nun from offing 5 band members otherwise known as "The Ex Choir Boys." But when it is determined that the detectives can't solve the case on their own, expert F.B.I. profiler Agent Peccant (comedian Ant) is assigned to the case. As the details of the case slowly emerge the police determine that that the "nun" may only be a silent witness to the grisly murders. The task force then turns its attention on the Catholic Church and a suspect group of Priests that have had a propensity for "cleansing the souls" of innocent young choir boys.

An original drama by novelist Mark Haddon about two teenage brothers: angst-ridden David and Ben, who has Downs Syndrome.

Bob and Joanna, both over 40 years old, have a baby with the Down syndrome. Their doctor advises them to give the child away, not to "waste their time" with a kid with a mental deficiency. But the parents decide to keep their son, to allow him a life with dignity and to support him as best as possible. And their devotion bears fruit...

Two men being questioned in a police station on Christmas Eve both confess to the murder of a cop. With both stories seeming plausible, an investigator is called in to determine which suspect is telling the truth - and why the other one is lying. Crime drama, starring James Earl Jones and Jason Bateman.

Life Goes On is a television series that aired on ABC from September 12, 1989, to May 23, 1993. The show centers on the Thatcher family living in suburban Chicago: Drew, his wife Elizabeth, and their children Paige, Rebecca, and Charles, who is known as Corky. Life Goes On was the first television series to have a major character with Down syndrome.

Patrick Jane, a former celebrity psychic medium, uses his razor sharp skills of observation and expertise at "reading" people to solve serious crimes with the California Bureau of Investigation.

Highly skilled Detective Inspector Jane Tennison battles to prove herself in a male dominated world.

Silent Witness is a British crime thriller series focusing on a team of forensic pathology experts and their investigations into various crimes.

P.S. I Luv U is an American crime drama series. The title derived from the phone number of fictitious Palm Security and Investigations, which was 774-5888, which can be reached by dialing "PSI-LUVU" on a standard North American telephone.

No Hiding Place is a British television series that was produced at Wembley Studios by Associated-Rediffusion for the ITV network between 16 September 1959 and 22 June 1967. It was the sequel to the series Murder Bag and Crime Sheet, all starring Raymond Francis as Detective Superintendent, later Detective Chief Superintendent Tom Lockhart.

Born This Way follows a group of young adults with Down syndrome as they pursue their dreams and explore their friendships, romantic relationships, and work.

Sex, lies and a tale too twisted to be real surround the murder of Gregg Smart. Who Killed Him? And why? On May 1, 1990, 22-year-old teacher Pamela Smart finds her husband Gregg dead on the floor of their southern New Hampshire condo, leaving the town of Derry stunned. Scouring the region for clues, police shift their attention to Gregg's grieving widow, Pamela Smart, who has been making curious television appearances publicizing her plight. When investigators discover Pamela has been having a sordid affair with high school student, Billy Flynn, a complicated web of lies and deceit unravel, revealing one of the most scandalous crimes of the century. Now, leading true crime network Investigation Discovery (ID) delves into the case in Pamela Smart: An American Murder Mystery. From the tawdry affair, to teenage assassins, to the explosive nationally televised trial, this case transfixed the entire nation as Pamela Smart emerged as the original Black Widow.

Dex Parios is a strong, assertive, and unapologetically sharp-witted Army veteran working as a P.I. in Portland, Oregon. With a complicated personal history and only herself to rely on, she solves other people’s messes with a blind eye toward her own.

The remarkable story of how murderer Charles Sobhraj was captured. As the chief suspect in unsolved murders of young Western travellers across India, Thailand and Nepal’s ‘Hippie Trail’ in 1975 and 1976, Sobhraj had repeatedly slipped from the grasp of authorities worldwide to become Interpol's most wanted man, with arrest warrants on three different continents.

A detective in a small Pennsylvania town investigates a local murder while trying to keep her life from falling apart.

When a killer wants you dead, there's one place to search: home sweet home. With the twist of a lock, your home should be your sanctuary. For some, it becomes a hunting ground - and no lock, security system or call to 911 will save them.

Exploring the intricacies of producing irrefutable evidence, conducting interviews and finding ways to make the guilty confess.

Series re-examining the evidence from British au pair Louise Woodward's murder trial 25 years ago. Includes unprecedented access to witnesses, the defence team, the prosecution and members of the jury who decided her fate.

Cha Moosik runs a casino bar, only to flee to the Philippines due to a crackdown by the National Tax Service. He launches a full-fledged casino business, and strategizes winning over the political and business circles in the Philippines. However, he is suddenly framed as a suspect in Min Seokjun's death, and is tracked by Oh Seunghoon of the Korean Desk. Betrayal is rampant in the presence of money.