Best movies like Love & Other Drugs

Addicted to one-night stands or dependent on one another?

A unique, carefully handpicked, selection of the best movies like Love & Other Drugs Starring Jake Gyllenhaal, Anne Hathaway, Oliver Platt, Hank Azaria, and more. If you liked Love & Other Drugs then you may also like: One Day, 40 Days and 40 Nights, The Ugly Truth, The Wedding Date, What Love Is and many more popular movies featured on this list. You can further filter the list even more or get a random selection from the list of similar movies, to make your selection even easier.

Maggie is an alluring free spirit who won't let anyone – or anything – tie her down. But she meets her match in Jamie, whose relentless and nearly infallible charm serves him well with the ladies and the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: love.

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Know any good movies to watch like Love & Other Drugs 2010. With a similar plot or stoyline. Suggest it.

One Day

A romantic comedy centered on Dexter and Emma, who first meet during their graduation in 1988 and proceed to keep in touch regularly. The film follows what they do on July 15 annually, usually doing something together.

40 Days and 40 Nights

Matt Sullivan's last big relationship ended in disaster and ever since his heart's been aching and his commitment's been lacking. Then came Lent, that time of year when everybody gives something up. That's when Matt decides to go where no man's gone before and make a vow: No sex. Whatsoever. For 40 straight days. At first he has everything under control. That is until the woman of his dreams, Erica, walks into his life.

The Ugly Truth

A romantically challenged morning show producer is reluctantly embroiled in a series of outrageous tests by her chauvinistic correspondent to prove his theories on relationships and help her find love. His clever ploys, however, lead to an unexpected result.

The Wedding Date

With the wedding of her younger sister fast approaching, Kat Ellis faces the undesirable prospect of traveling alone to London for the ceremony. While this is bad enough, Jeffrey, the man who left her as they moved closer to marriage, happens to be the groom's best man. Determined to show everyone -- most of all Jeffrey -- that her romantic life is as full and thrilling as ever, Kat hires a charming male escort as her date.

What Love Is

It's Valentine's Day and Tom has big plans. He's about to get engaged and has a surprise party planned to share the good news with friends. But things take a turn for the worse. Tom returns home only to discover his girlfriend has packed up and left him. Now, instead of a surprise party, the surprise is on Tom. Fortunately, his friends are there to help him make sense of it all.

What's Your Number?

Ally Darling is realizing she's a little lost in life. Her latest romance has just fizzled out, and she's just been fired from her marketing job. Then she reads an eye-opening magazine article that warns that 96 percent of women who've been with 20 or more lovers are unlikely to find a husband. Determined to turn her life around and prove the article wrong, Ally embarks on a mission to find the perfect mate from among her numerous ex-boyfriends.

When Harry Met Sally...

During their travel from Chicago to New York, Harry and Sally debate whether or not sex ruins a friendship between a man and a woman. Eleven years later, and they're still no closer to finding the answer.

No Strings Attached

Emma is a busy doctor who sets up a seemingly perfect arrangement when she offers her best friend Adam a relationship with one rule: No strings attached. But when a fling becomes a thing, can sex friends stay best friends?

Normal Adolescent Behavior

High school student Wendy has an odd relationship with her five friends: They're openly sexual with each other, swapping partners every week. But this is all thrown into turmoil when she meets Sean, a new student in school who has a crush on her. Wendy wants to be with Sean, but doesn't want to disappoint her friends, whom she has known since grade school. When she does decide to leave them, her best friend, Billie, threatens revenge.

Killing Me Softly

A woman grows suspicious of her controlling husband after she discovers secrets about the women in his past.

Autumn in New York

Autumn in New York follows the sexual exploits of Will Keane - New York restaurateur, infamous verging-on-50 playboy, master of the no-commitment seduction - until he runs into an unexpected dead end when he meets Charlotte Fielding. Charlotte is half Will's age and twice his match, a 21 year-old free spirit yearning to get out and taste the excitement of adult life.

The Back-Up Plan

When Zoe tires of looking for Mr. Right, she decides to have a baby on her own. But on the day she's artificially inseminated, she meets Stan, who seems to be just who she's been searching for all her life. Now, Zoe has to figure out how to make her two life's dreams fit with each other.

The Cabin Movie

Three couples travel to a secluded cabin in an attempt to revitalize their lives through bizarre games of sexual dysfunction....and all heck breaks loose!

Crazy, Stupid, Love.

Cal Weaver is living the American dream. He has a good job, a beautiful house, great children and a beautiful wife, named Emily. Cal's seemingly perfect life unravels, however, when he learns that Emily has been unfaithful and wants a divorce. Over 40 and suddenly single, Cal is adrift in the fickle world of dating. Enter, Jacob Palmer, a self-styled player who takes Cal under his wing and teaches him how to be a hit with the ladies.

Good Luck Chuck

Cursed since childhood, dentist Charlie Logan cannot find the right woman. Even worse, he learns that each of his ex-girlfriends finds true love with the man she meets after her relationship with him ends. Hearing of Charlie's reputation as a good-luck charm, women from all over line up for a quick tryst. But when Charlie meets the woman of his dreams, he must find a way to break the curse or risk losing her to the next man she meets.

Young People Fucking

On a Tuesday night, five couples have separate sexual adventures. Matt and Kris, friends for years, want to have an only-once, no-strings good time. Abby and Andrew, married, celebrate his birthday, but it's marred by angst and miscommunication. Mia and Eric are exes, making sure they are over each other. Jaime and Ken work together and this is a first date. Inez and Gord invite his roommate, Dave, to join them. By the time each couple has gone through a prelude, foreplay, sex, an interlude, orgasm, and afterglow, they've answered basic questions: can sex be anonymous, are we bored, is our marriage really finished, does anyone tell the truth, and how do we make someone happy?

How to Lose a Guy in 10 Days

It’s the battle of wills, as Andie (Kate Hudson) needs to prove she can dump a guy in 10 days, whereas Ben (Matthew McConaughey) needs to prove he can win a girl in 10 days. Now, the clock is ticking - and the wildly entertaining comedy smash is off and running in this irresistible tale of sex, lies and outrageous romantic fireworks!

He's Just Not That Into You

Remember that really cute girl/guy who said they'd call – and didn't? Maybe they lost your number. Maybe they're in the hospital. Maybe they're awed by your looks, brains or success. Or maybe... They're just not that into you.

Lie with Me

Happily unattached, the sexually voracious Leila satisfies her desires with a host of rapidly changing bed partners, unconcerned about the emotional consequences. But that all changes when she meets an artist looking for a deeper commitment.

P.S. I Love You

A young widow discovers that her late husband has left her 10 messages intended to help ease her pain and start a new life.

Two Moon Junction

A young Southern débutante temporarily abandons her posh lifestyle and upcoming, semi-arranged marriage to have a lustful and erotic fling with a rugged drifter who works at a local carnival.

Dot the I

Young lovers in London are wrapped up in a love triangle that may not be exactly what it seems. Carmen, a beautiful Spanish woman with a tendency to lose her temper at the drop of a hat, is about to be married to Barnaby, a caring, wealthy, but slightly boring Englishman. While out with friends on her 'hen night' she encounters a stranger who suddenly sparks a passion that has been sleeping within her. As her wedding date approaches, she finds herself struggling to put this newcomer out of her mind, but his effect on her keeps growing stronger. What is it that he sees in her, and why does she feel like she's being pushed inevitably into his arms?

Friends with Benefits

Dylan and Jamie think it's going to be easy to add the simple act of sex to their friendship, despite what Hollywood romantic comedies would have them believe. They soon discover however that getting physical really does always lead to complications.

Going the Distance

Erin and Garrett are very much in love. When Erin moves to San Francisco to finish her journalism degree and Garrett stays behind in New York to work in the music industry, they gamely keep the romance alive with webcams and frequent-flyer miles. But just when it seems the lovers will soon be reunited, they each score a big break that could separate them for good.

Sex and the City

A New York writer on sex and love is finally getting married to her Mr. Big. But her three best girlfriends must console her after one of them inadvertently leads Mr. Big to jilt her.

Casual Sex?

Two girls go away to a holiday resort looking for a change of pace, hoping to meet some nice men for a change. They discover that they can't find the perfect man, and this forces them to reconsider their attitudes to men in general.

Letters to Juliet

An American girl on vacation in Italy finds an unanswered "letter to Juliet" -- one of thousands of missives left at the fictional lover's Verona courtyard, which are typically answered by the "secretaries of Juliet" -- and she goes on a quest to find the lovers referenced in the letter.

A Lot Like Love

On a flight from Los Angeles to New York, Oliver and Emily make a connection, only to decide that they are poorly suited to be together. Over the next seven years, however, they are reunited time and time again, they go from being acquaintances to close friends to ... lovers?

The Party at Kitty and Stud's

Kitty and Stud are lovers. They enjoy a robust sex-life, which includes fellatio and light S&M, specifically, Stud belt-whipping Kitty. Three women come over for a party and Stud services them, one after the other.

The Proposal

When she learns she's in danger of losing her visa status and being deported, overbearing book editor Margaret Tate forces her put-upon assistant, Andrew Paxton, to marry her.

Sex and the City 2

Carrie, Charlotte, and Miranda are all married now, but they're still up for a little fun in the sun. When Samantha gets the chance to visit one of the most extravagant vacation destinations on the planet and offers to bring them all along, they surmise that a women-only retreat may be the perfect excuse to eschew their responsibilities and remember what life was like before they decided to settle down.

Spread

A gigolo must contend with the prospect that he has found true love.

A Little Bit of Heaven

A guarded woman finds out she's dying of cancer but, when she meets her match, the threat of falling in love is scarier than death.

The Long Weekend

Cooper is an actor who sees life as one big party, while Ed is in advertising and takes life too seriously. When Ed gets stressed over a deadline he has to meet, his brother Cooper works hard in trying to get his brother hooked up with a girl, thus a long weekend of stress and beautiful women, culminating in Ed meeting, and making love to, the woman of his dreams.

What Boys Like

Things get crazy fro three groomsmen who make a bet on their way to their best friend's wedding. Can the dedicated swinger resist the ultimate temptation and remain celibate during the hottest weekend on his life? Can the serial monogamist actually go through with his first one night stand? It's up to the stunning bridesmaids who are ready for little misadventures of their own in their wedding that brings new meaning to the words LOVE, HoNOR and OBEY.

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