Best movies like Osmosis Jones

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A unique, carefully handpicked, selection of the best movies like Osmosis Jones Starring Chris Rock, Laurence Fishburne, David Hyde Pierce, Brandy Norwood, and more. If you liked Osmosis Jones then you may also like: Nutty Professor II: The Klumps, Ride Along, Ride Along 2, Are We There Yet?, Atlantis: The Lost Empire and many more popular movies featured on this list. You can further filter the list even more or get a random selection from the list of similar movies, to make your selection even easier.

A white blood cell policeman, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.

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Nutty Professor II: The Klumps

The hilarity begins when professor Sherman Klump finds romance with fellow DNA specialist, Denise Gaines, and discovers a brilliant formula that reverses aging. But Sherman's thin and obnoxious alter ego, Buddy Love, wants out...and a big piece of the action. And when Buddy gets loose, things get seriously nutty.

Ride Along

For the past two years, high-school security guard Ben has been trying to show decorated APD detective James that he's more than just a video-game junkie who's unworthy of James' sister, Angela. When Ben finally gets accepted into the academy, he thinks he's earned the seasoned policeman's respect and asks for his blessing to marry Angela. Knowing that a ride along will demonstrate if Ben has what it takes to take care of his sister, James invites him on a shift designed to scare the hell out of the trainee. But when the wild night leads them to the most notorious criminal in the city, James will find that his new partner's rapid-fire mouth is just as dangerous as the bullets speeding at it.

Ride Along 2

As his wedding day approaches, Ben heads to Miami with his soon-to-be brother-in-law James to bring down a drug dealer who's supplying the dealers of Atlanta with product.

Are We There Yet?

The fledgling romance between Nick, a playboy bachelor, and Suzanne, a divorced mother of two, is threatened by a particularly harrowing New Years Eve. When Suzanne's work keeps her in Vancouver for the holiday, Nick offers to bring her kids to the city from Portland, Oregon. The kids, who have never liked any of the men their mom dates, are determined to turn the trip into a nightmare for Nick.

Atlantis: The Lost Empire

The world's most highly qualified crew of archaeologists and explorers is led by historian Milo Thatch as they board the incredible 1,000-foot submarine Ulysses and head deep into the mysteries of the sea. The underwater expedition takes an unexpected turn when the team's mission must switch from exploring Atlantis to protecting it.

Bad Boys

Marcus Burnett is a hen-pecked family man. Mike Lowry is a foot-loose and fancy free ladies' man. Both are Miami policemen, and both have 72 hours to reclaim a consignment of drugs stolen from under their station's nose. To complicate matters, in order to get the assistance of the sole witness to a murder, they have to pretend to be each other.

Scooby-Doo! and the Cyber Chase

When Scooby and the gang get trapped in a video game created for the gang, they must fight against the 'Phantom Virus.' To escape the game they must go level by level and defeat the game once and for all.

Lilo & Stitch

As Stitch, a runaway genetic experiment from a faraway planet, wreaks havoc on the Hawaiian Islands, he becomes the mischievous adopted alien "puppy" of an independent little girl named Lilo and learns about loyalty, friendship, and ʻohana, the Hawaiian tradition of family.

G-Force

A team of trained secret agent animals, guinea pigs Darwin, Hurley, Juarez, Blaster, mole Speckles, and fly Mooch takes on a mission for the US government to stop evil Leonard Saber, who plans to destroy the world with household appliances. But the government shuts them down and they are sentenced to a pet shop. Can they escape to defeat the villain and save the world?

The Muppets

When Kermit the Frog and the Muppets learn that their beloved theater is slated for demolition, a sympathetic human, Gary, and his puppet brother, Walter, swoop in to help the gang put on a show and raise the $10 million they need to save the day.

Big Hero 6

A special bond develops between plus-sized inflatable robot Baymax, and prodigy Hiro Hamada, who team up with a group of friends to form a band of high-tech heroes.

Collision Course

A Japanese investigator and a Detroit cop team up to track down a stolen prototype turbocharger.

The Cowboy Way

Two championship rodeo partners travel to New York to find their missing friend, Nacho Salazar who went missing there.

Epic

A teenager finds herself transported to a deep forest setting where a battle between the forces of good and the forces of evil is taking place. She bands together with a rag-tag group characters in order to save their world—and ours.

Teenage Mutant Ninja Turtles: Out of the Shadows

After supervillain Shredder escapes custody, he joins forces with mad scientist Baxter Stockman and two dimwitted henchmen, Bebop and Rocksteady, to unleash a diabolical plan to take over the world. As the Turtles prepare to take on Shredder and his new crew, they find themselves facing an even greater evil with similar intentions: the notorious Krang.

Wild Wild West

Legless Southern inventor Dr. Arliss Loveless plans to rekindle the Civil War by assassinating President U.S. Grant. Only two men can stop him: gunfighter James West and master-of-disguise and inventor Artemus Gordon. The two must team up to thwart Loveless' plans.

Ghost Rider: Spirit of Vengeance

When the devil resurfaces with aims to take over the world in human form, Johnny Blaze reluctantly comes out of hiding to transform into the flame-spewing supernatural hero Ghost Rider -- and rescue a 10-year-old boy from an unsavory end.

Sausage Party

Frank leads a group of supermarket products on a quest to discover the truth about their existence and what really happens when they become chosen to leave the grocery store.

Men in Black

After a police chase with an otherworldly being, a New York City cop is recruited as an agent in a top-secret organization established to monitor and police alien activity on Earth: the Men in Black. Agent Kay and new recruit Agent Jay find themselves in the middle of a deadly plot by an intergalactic terrorist who has arrived on Earth to assassinate two ambassadors from opposing galaxies.

Stuart Little

The adventures of a heroic and debonair stalwart mouse named Stuart Little with human qualities, who faces some comic misadventures while searching for his lost bird friend and living with a human family as their child.

Here Comes the Boom

A high school biology teacher moonlights as a mixed-martial arts fighter in an effort to raise money to save the school's music program.

Jimmy Neutron: Boy Genius

Jimmy Neutron is a boy genius and way ahead of his friends, but when it comes to being cool, he's a little behind. All until one day when his parents, and parents all over Earth are kidnapped by aliens, it's up to him to lead all the children of the world to rescue their parents.

Sinbad: Legend of the Seven Seas

The sailor of legend is framed by the goddess Eris for the theft of the Book of Peace, and must travel to her realm at the end of the world to retrieve it and save the life of his childhood friend Prince Proteus.

Downtown

Officer Alex Kearney patrols an upscale neighborhood in Philadelphia, where he pulls over a well-connected white collar executive who promises to get even with the policeman. Soon, Kearney learns that he is off the cushy suburban beat and must now work in the deadliest precinct in Philly, where he is partnered with tough veteran cop Dennis Curran. Tensions are high between them, but Kearney soon proves he can play just as rough as the crooks.

The SpongeBob SquarePants Movie

There's trouble brewing in Bikini Bottom. Someone has stolen King Neptune's crown, and it looks like Mr. Krab, SpongeBob's boss, is the culprit. Though he's just been passed over for the promotion of his dreams, SpongeBob stands by his boss, and along with his best pal Patrick, sets out on a treacherous mission to Shell City to reclaim the crown and save Mr. Krab's life.

Monsters vs Aliens

When Susan Murphy is unwittingly clobbered by a meteor full of outer space gunk on her wedding day, she mysteriously grows to 49-feet-11-inches. The military jumps into action and captures Susan, secreting her away to a covert government compound. She is renamed Ginormica and placed in confinement with a ragtag group of Monsters...

Little Man

After leaving the prison, the dwarf criminal Calvin Sims joins to his moron brother Percy to steal an expensive huge diamond in a jewelry for the mobster Walken. They are chased by the police, and Calvin hides the stone in the purse of the executive Vanessa Edwards, whose husband Darryl Edwards wants to have a baby. Percy convinces Calvin to dress like a baby and be left in front of the Edwards's house to get inside the house and retrieve the diamond. Darryl and Vanessa keep Calvin for the weekend and decide to adopt him, while Walken threatens Darryl to get the stone back.

Midnight Run

A bounty hunter pursues a former Mafia accountant who embezzled $15 million of mob money. He is also being chased by a rival bounty hunter, the F.B.I., and his old mob boss after jumping bail.

The Man

A case of mistaken identity forces a Federal agent and a dental supply salesman to team up as they speed through the streets of Detroit to pull off a sting operation and solve the murder of the agent's former partner.

Hollow Point

Livingston is trying to merge the Russians, Chinese and Italian gangsters into one group with huge amounts of money and power. FBI agent Susan and DEA agent Max are trying to stop them.

Pokémon Detective Pikachu

In a world where people collect pocket-size monsters (Pokémon) to do battle, a boy comes across an intelligent monster who seeks to be a detective.

Hey Arnold! The Movie

Arnold and his friends must recover a stolen document in order to prevent the neighborhood from being bulldozed.

Planet 51

When Earth astronaut Capt. Chuck Baker arrives on Planet 51 -- a world reminiscent of American suburbia circa 1950 -- he tries to avoid capture, recover his spaceship and make it home safely, all with the help of an empathetic little green being.

Hop

E.B., the Easter Bunny's teenage son, heads to Hollywood, determined to become a drummer in a rock 'n' roll band. In L.A., he's taken in by Fred after the out-of-work slacker hits E.B. with his car.

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