Best movies like Serum

The moment you are injected, the chaos begins.

A unique, carefully handpicked, selection of the best movies like Serum Starring Derek Phillips, Dennis O'Neill, Liz Cardenas Franke, David H. Hickey, and more. If you liked Serum then you may also like: Unseen Evil, The Werewolf, Jungle Jim, Knucklehead, Anaconda 3: Offspring and many more popular movies featured on this list. You can further filter the list even more or get a random selection from the list of similar movies, to make your selection even easier.

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While searching for a "cure all" serum, Dr. Edward Kanopolus, "Dr. K", is being pressured for results by the pharmaceutical company funding the project. With time running out, tragedy and desperation drive him to make decisions that will jeopardize the lives of everyone around him and ultimately unleash a terrifying monster on a killing spree.

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Unseen Evil

A group of hikers led by a college professor are searching the woods for an ancient Indian burial mound. When they discover a likely site, three members of the group reveal themselves to be grave looters, and tie up the others so they can keep the valuable artefacts for themselves. In the course of ransacking the mound, one of them stumbles across a cursed crown that unleashes the mound's guardian: an invisible monster that begins attacking everyone it finds. Will anyone make it back to civilization alive?

The Werewolf

The arrival in a small mountain town of a dissheveled stranger launches a series of murders committed by some sort of animal. As the town doctor and his daughter attempt to help the stranger, the sheriff investigates the murders; and they uncover a sinister experiment involving two rogue scientists, a car accident victim, his wife and children, and a serum that causes a man to turn into a ravaging werewolf.

Jungle Jim

Lady scientist, Hilary Parker is searching for a rare drug to help combat polio. Opportunist Bruce Edwards joins the quest but is actually after gold and buried treasure.

Knucklehead

When his brother disappears, mentally disabled Langston Bellows (Gbenga Akinnagbe) is left without a protector in Brooklyn's housing projects. Now under the control of his abusive mother (Alfre Woodard) Langston must take his future into his own hands. He sets out to find the one doctor he believes can cure him, a celebrity magazine columnist who touts questionable prescription drug cocktails. If Langston can become "mentally excellent", it will mean moving into an apartment of his own with his girlfriend, who may herself be a creation of his wishful thinking. Landing in the unscrupulous world of pharmaceutical marketing, the search for his mysterious doctor and hero leads to some unwanted discoveries. Langston strives for independence from his prior life; from his mother, from his neighborhood and from his fractured mind - while all around him people are not who they seem.

Anaconda 3: Offspring

Cancer-terminal tycoon Peter Murdoch's secret Wexel Hall Pharmaceuticals lab has developed a blood orchid extract cure. To examine why it works optimally in snakes, they also bread a super-anaconda strain. But the original pair escapes, leaving a bloody trail of human corpses. Murdoch runs, instructing his staff to clean up. They keep failing and being eaten like unsuspecting locals, some alive, even after enlisting ruthless big game hunter Hammett. The fast-growing pregnant monster sheds its skin, thus disabling the only tracking device they have.

The Ape

Dr. Bernard Adrian is a kindly scientist who seeks to cure a young woman's polio. He needs human spinal fluid to complete the formula for his experimental serum. Meanwhile, a vicious circus ape has broken out of its cage, and is terrorizing the townspeople. Can there be a connection?

The Perfect Boss

Beautiful, successful Jessica Slade is used to getting what she wants whether she has to use her brains, charm, or body to do it. So when Jessica is hired by Mickelson Pharmaceuticals to fast-track a drug that will keep the company afloat, she’s confident she can convince the FDA to make it happen. What she doesn’t know, however, is that one of the researchers, Don, has discovered that the drug is killing people...

Broken Trust

Sophie Anderson is the lead attorney on an intellectual property case against a corrupt pharmaceutical company. When her mentor and boss is kidnapped, she becomes a pawn in an elaborate scheme that jeopardizes her case and more.

Death Machine

Chaank Armaments is experimenting with the ultimate fighting machine which is part human - part machine. So far, the Hardman project has been unreliable and has killed a number of innocent people. The genius behind this project is Jack who lives in a world of models, toys and magazines. When he is fired by Cale for killing a few corporate officers, he unleashes the ultimate killing machine called the 'Warbeast' against Cale and those who would help her.

Deep Blue Sea 2

When shark conservationist Dr. Misty Calhoun is invited to consult on a top-secret project run by pharmaceutical billionaire Carl Durant, she is shocked to learn that the company is using unpredictable and highly aggressive bull sharks as its test subjects, which soon break loose and cause havoc.

Devil's Playground

As the world succumbs to a zombie apocalypse, Cole - a hardened mercenary - is chasing the one person who can provide a cure. Not only to the plague but to Cole's own incumbent destiny.

Dr. Black, Mr. Hyde

A doctor in a Watts clinic takes his own medicine and becomes a monstrous white killer of hookers.

God Bless America

Fed up with the cruelty and stupidity of American culture, an unlikely duo goes on a killing spree, killing reality TV stars, bigots and others they find repugnant.

Phase IV

Journalism student Simon Tate thinks it's strange when four students at the university suddenly die in "unrelated" accidents. When his friend, Dr. Benjamin Roanic, becomes the prime suspect and is suddenly murdered, Simon sets out to prove his innocence. He soon discovers the students were Roanic's test subjects in a secret drug test program, and had been cured of AIDS. He is forced to run for his life, when a pharmaceutical company tries to prevent him from revealing the truth behind "Phase IV".

Island of Terror

A small island community is overrun with creeping, blobbish, tentacled monsters which liquefy and digest the bones from living creatures. The community struggles to fight back.

Mega Python vs. Gatoroid

A fanatical animal rights activist releases giant pythons into the Everglades, believing the wild animals should be set free. When they start decimating the native animal population, an over-zealous park ranger feeds experimental steroids to wild alligators so they can fight back. The giant pythons and gargantuan alligators go on a killing spree, and it is now left up to the two feuding women to put aside their differences to put a stop to the creatures and the destruction.

Slow Burn

A woman's lifelong pursuit of lost family diamonds is interrupted by the appearance of two escaped convicts.

Nightbeasts

A father and son on a weekend hunting trip encounter supernatural horror in the woods.

Virus Shark

A shark bite spreads a virus across the globe, turning the world upside down. Deep below the ocean, a group of researchers race against time to find a cure. Something has infected the lab technicians and it’s a race against time to reach the surface with an antidote before they are all killed by themselves and the sharks lurking inside the test pool and outside in the ocean.

Mom

During a time when the city of Los Angeles is terrorized by animal attack style murders, a kindly elderly lady provides a nomad with room and board. It turns out that he is a werewolf and is responsible for the recent killings. He bites the elderly woman, turning her into a hungry werewolf. Now her adult son must try to prevent the both of them from doing any more harm.

Monsters in the Woods

A micro-budget movie crew treks into the wilderness to shoot horror scenes for their unsellable indie-drama. They soon find themselves in the midst of their own real horror movie, as they are hunted by a large group of creatures.

Mosquito Man

Police lieutenant detective Thomas 'Thom' Randall's steady girl-friend, Dr. Jennifer 'Jen' Allen, is Dr. Aaron Michaels's main assistant on his pharmaceutical firm Bellion's research program to cure the highly contagious, fatal infection Guinin. A convicted murderer, whom Thom arrested, is one of their special drug test subjects, but escapes. The convict and Jen are affected by radioactively altered DNA from an experimental reactor used on mosquitoes which transfer quinine. The convict soon mutates into a mosquito-like monster, which sucks its victims dry. By the time Thom and his junior murder brigade partner Charlie Morrison figure out what happens, Jen starts mutating herself.

The Intruder Within

When drillers on an offshore oil rig dredge up several prehistoric eggs, one man is attacked by what appears to be an unidentified deep-sea creature protecting them. Soon, strange symptoms and behaviors become apparent among the crew and one of the creatures grows to adult-size.

Living Hell

In a top secret Cold War military project an unstoppable, malignant organism who feeds on light and energy is unleashed threatening to destroy everything in its path.

Mongolian Death Worm

When an American oil company sets up an experimental drilling plant out in the vast deserts of Mongolia, they awaken a nest. The deadly creatures begin to breed and spread, devouring everyone in their path. The only person who can stop them is treasure hunter and adventure seeker who spent his life searching for a legendary tomb, fabled to be protected by the Death Worms. He knows he must do what he can to kill the creatures, but stopping these monsters may mean destroying his life's work forever!

The Jurassic Dead

A crack-pot scientist aligns with the Axis of Evil to bring down the United States with EMP blasts, toxic zombification gas and by unleashing the ultimate undead killing monstrosity: the Z-REX. When a hot-wired militia squad and a crew of college hipsters are thrown together to do something about it, chaotic Predator-Thunder action runs amok.

Jurassic Shark

When an oil company unwittingly unleashes a prehistoric shark from its icy prison, the Jurassic killer maroons a group of art thieves and a group of college students on an abandoned island

Project D: Classified

PROJECT D: CLASSIFIED concerns a top secret retrieval mission to the Moon which ends with the spacecraft crashing back to Earth. At that point, the search for the classified contents from the mission begins, bringing together an unlikely group of people: a quantum physics professor, an investigative reporter, Men in Black known as "The Silencers," a writer, a psychic medium - and an astronaut who is half-man, half-monster who goes on a killing spree looking for the missing contents. Time is running out for all of them, and for Earth, because the mysterious contents from the spacecraft are also being hunted by those from whom they were taken...the aliens themselves.

Slay Belles

While urban exploring in an abandoned amusement park, three cosplaying girls accidentally unleash the vicious holiday beast known as Krampus. With the help of Santa Claus, can these girls stop Krampus from his killing spree?

Three Sisters: Searching For A Cure

Follows the lives of three sisters affected by one having ALS, finding a cure, and the foundation formed to combat the disease, Project ALS.

Sweetwater

The story of two childhood friends who have grown apart and are suddenly thrust back into each others lives when a parent develops cancer. They join forces to find the cure but soon realize their lives are danger if they expose the truth.

Strange Blood

When a brilliant but obsessive scientist goes to extremes to develop a universal cure for all disease, he finds himself infected with a bizarre parasite that begins to transform him into a bloodthirsty madman. Time running out, he must find a way to stop the monster that is growing within and prevent the rest of the world from being "cured."

The Shattering

In the dead of night, Donovan drives with his girlfriend, Lucy and several friends to a secret rendezvous in the woods. They believe they are meeting a "healer" who can cure Lucy's cancer, but they grow suspicious when a booby-trap in the road forces them to stop short of their destination. when the driver gets out to investigate he is brutally killed and dragged from the car. Terrified, the remaining friends run for their lives to a deserted cabin, dodging the paramilitary commandos that hunt them as well as the deadly creatures that slaughtered their friends. As the friends die, one by one, they realize too late that Donovan has set them up as bait in exchange for a magic elixir he believes will heal Lucy, but even Donovan is not prepared to pay the price for Lucy's cure.

To End All War: Oppenheimer & the Atomic Bomb

Explore how one man's relentless drive and invention of the atomic bomb changed the nature of war forever, led to the deaths of hundreds of thousands of people and unleashed mass hysteria.

CREATE OR DIE

In an industry that is becoming increasingly competitive, what drives indie filmmakers to keep creating their art, even when there is no promise of money or fame? CREATE OR DIE explores the insatiable passion to create despite the overwhelming odds through the lens of South Carolina writer and filmmaker David Axe, as he and his band of cast and crew head out into the backwoods of Georgia to shoot his low budget passion project ACORN. But when tragedy strikes on set, doubt and tension threaten to bring an end to their production and their dreams.

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