Best movies like Man's Best Friend

Companion. Protector. Killer.

A unique, carefully handpicked, selection of the best movies like Man's Best Friend Starring Ally Sheedy, Lance Henriksen, Robert Costanzo, Fredric Lehne, and more. If you liked Man's Best Friend then you may also like: Watchers II, Webs, Night of the Lepus, Orca, Raptor and many more popular movies featured on this list. You can further filter the list even more or get a random selection from the list of similar movies, to make your selection even easier.

A dog turns from man's best friend into man's worst nightmare as he attacks everything that moves.

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Watchers II

A genetically re-engineered dog develops a psychic link with a monster created in a lab experiment which goes awry.

Webs

Richard Greico leads a team of electrical workers who stumble across a terrifying parallel universe. While investigating a strange power source in an abandoned building, the workers find themselves sucked into an underworld teeming with massive, man-eating, spider-like monsters. The bloodthirsty arachnid-human hybrids stalk and kill their victims one by one, leaving the dwindling group of survivors to fight back with just their wits and a handful of primitive weapons.

Orca

After witnessing the killing of his mate and offspring at the hands of a reckless Irish captain, a vengeful killer whale rampages through the fisherman's Newfoundland harbor. Under pressure from the villagers, the captain, a female marine biologist and an Indigenous tribalist venture after the great beast, who will meet them on its own turf.

Raptor

When a series of unexplained vicious animal attacks strikes his community, Sheriff Jim Tanner and his assistant Barbara trace them back to a Dr. Hyde, a former military researcher whose government funding for a dinosaur cloning project was cut. When the Pentagon discovers Hyde obtained foreign backing to continue his experiments, they send in a strike team to save Tanner and Barbara and stop Hyde.

Rogue

From the director of Wolf Creek comes this terrifying look at nature's perfect killing machine. When a group of tourists stumble into the remote Australian river territory of an enormous crocodile, the deadly creature traps them on a tiny mud island with the tide quickly rising and darkness descending. As the hungry predator closes in, they must fight for survival against all odds.

The Kindred

Amanda's deathbed request to her son, John, was for him to destroy all the lab notes etc. from her last experiment. She also blurts out he had a brother. At the funeral John meets Melissa, who claims to be his mother's biggest fan. Together with some of John's friends they go to Amanda's house, but none are prepared for what they find there.

King Cobra

30 feet of pure terror is the result of an experimental drug used in a biochemical lab and this mutated nightmare is pure evil! Half-African cobra and half-diamondback, he's 30 feet long with a giant appetite for terror.

Komodo vs. Cobra

A team of environmentalists, including a reporter, her camera man, and an environmentalist's famous girlfriend charter a boat and with the captain, sail to a military island. They suspect the island is hosting to illegal activities. Upon arrival, however, they find no one. They finally reach a deserted house, where they find Dr. Susan Richardson, who tells them that everyone on the island is dead, including her father. Richardson's team were working on a compound that could make edible plants grow to super size, however the military intervened with plans of their own. They wanted to test the compound's effects on animals, and proceeded to feed it to several komodo dragons and cobras.

Anacondas: Trail of Blood

A genetically created Anaconda, cut in half, regenerates itself into two new aggressive giant snakes, due to the Blood Orchid.

6.7 / 10 1996 Horror
suggested by: user368q1fbrn93

Bad Moon

One man's struggle to contain the curse he hides within... and his last-ditch attempt to free himself with the love of family. But when it looks as if he is losing his battle, and endangering all he holds most dear, the family dog, Thor, is the last hope for his family's survival... and the end to his Werewolf curse.

The Bat People

Dr. John Beck, recently married, decides to take his wife, Cathy, spelunking in Carlsbad Cavern. While there, Dr. Beck, who specializes in bats, is bitten by a fruit bat. He is then, inexplicably, transformed into a vampire bat. While he escapes and seeks help from another doctor, it is clear the treatments are not working. In fact, they are aggravating his condition. Dr. Beck unwittingly goes on a killing spree, catching the attention of Sergeant Ward.

Bats

Genetically mutated bats escape and it's up to a bat expert and the local sheriff to stop them.

Bats: Human Harvest

A group of Delta Force soldiers, accompanied by a CIA agent, are sent to the Belzan forest in Chechnya in search of a rogue American weapons researcher, Dr. Benton Walsh. As they search for Walsh's camp, they are attacked by genetically-altered carnivorous bats. The survivors attempt to reach helicopter extraction but encounter various challenges, including Chechen rebels.

The Breed

Brothers John and Matt have inherited an island cabin from their recently deceased uncle. Along with Matt's girlfriend, Nicki, and other mutual friends, the siblings travel to the cabin for a relaxing weekend getaway. But, not long after arriving, the group is besieged by ravenous dogs. They watch in horror as another vacationer, Luke, is eaten alive. Soon, they discover a training facility where the dogs have been bred to kill.

The Island of Dr. Moreau

A shipwrecked sailor stumbles upon a mysterious island and is shocked to discover that a brilliant scientist and his lab assistant have found a way to combine human and animal DNA—with horrific results.

Anacondas: The Hunt for the Blood Orchid

The blood orchid - a rare flower that could hold the secret of eternal life and be worth a fortune to the company that finds it first. Led by a pharmaceutical research team, a scientific expedition sets out to go and explore deep into the jungles of Borneo to locate and bring back samples of the legendary plant. Battling through rainstorms to make their way upriver, the group encounters poisonous insects and a ferocious crocodile, only to discover they're being stalked by an even greater danger: a gathering of giant anacondas. Heat-sensing, fifty-foot-long flesh eaters that will go after anyone that crosses in their path.

The Giant Spider Invasion

A black hole hits North Wisconsin and opens a door to other dimensions. Giant 15 meter spiders emerge from it, who have an appetite for human flesh! Dr. Jenny Langer and Dr. Vance from NASA try to save the world.

The Vindicator

An employee of a secret company operation becomes the victim of the company's special weapons project. He is transformed into a robotic killing machine that, because of his programming must destroy anything that comes near him.

Crocodile

A group of friends including Brady Turner, Claire and Duncan McKay go out on a boat trip on a lake in Southern California, but their joyful weekend turns into horror, when a giant killer crocodile searching for its stolen eggs, picks off anyone who gets in its way. Can they all escape in one piece or will they slowly and painfully fall to the mammoth reptile.

Deep Blue Sea

Researchers on the undersea lab Aquatica have genetically altered the brains of captive sharks to develop a cure for Alzheimer's disease. But there's an unexpected side effect: the sharks got smarter, faster, and more dangerous. After a big storm damages their remote research facility, they must fight for their lives.

Deep Blue Sea 2

When shark conservationist Dr. Misty Calhoun is invited to consult on a top-secret project run by pharmaceutical billionaire Carl Durant, she is shocked to learn that the company is using unpredictable and highly aggressive bull sharks as its test subjects, which soon break loose and cause havoc.

Cujo

A friendly St. Bernard named "Cujo" contracts rabies and conducts a reign of terror on a small American town.

Primeval

A news team is sent to Burundi to capture and bring home a legendary 25-foot crocodile. Their difficult task turns potentially deadly when a warlord targets them for death.

Frankenfish

When the body of a man is found completely destroyed in the swamps in Louisiana, the medical investigator Sam Rivers is assigned to investigate the murder. He travels with the biologist Mary Callahan to the location where the victim lived in a floating house and he meets his family and friends. They find that Chinese snake-heads genetically engineered that belong to a wealthy hunter are attacking and killing the locals. While the group fights to survive, the hunter Jeff arrives with his team to hunt the predators.

The Island of Dr. Moreau

A ship-wrecked man floats ashore on an island in the Pacific Ocean. The island is inhabited by a scientist, Dr. Moreau, who in an experiment has turned beasts into human beings.

Isolation

On a remote Irish farm, five people become unwilling participants in an experiment that goes nightmarishly wrong.

Ice Spiders

When a young ski team training for the Olympics arrives at the remote and isolated Lost Mountain Ski Resort to focus on training, they're thrilled to find a retired Olympic skier is there to help them train. But their plans are halted when a scientist working at a nearby government lab arrives with the horrifying news that a top secret Government project has produced giant spiders and they have escaped, killing and eating everything in sight.

Mimic: Sentinel

A man enclosed in a plastic bubble, his sister, and their best friend must defend an apartment complex from the mutant Judas Breed insects.

Pet Sematary II

The "sematary" is up to its old zombie-raising tricks again. This time, the protagonists are Jeff Matthews, whose mother died in a Hollywood stage accident, and Drew Gilbert, a boy coping with an abusive stepfather.

Python

Sleepy New Haven California is a small town with a big problem. A sixty foot slithering horror has arrived and shattered the town's tranquillity on it's path of death and destruction... Growing violent and more savage with each attack the gigantic creature soon becomes an unstoppable feeding machine raging beyond control of it's creator, leaving only the stripped bones of it's victims in it's wake.

Sabretooth

Using fossilized DNA, a scientist resurrects one of nature's most fearsome predators, a sabretooth tiger. Scientific ambition turns deadly, however, when the creature escapes and begins savagely stalking its prey - the human race.

5.3 / 10 2006 Horror
suggested by: user519khngxawr

Mulberry Street

A deadly infection breaks out in Manhattan, causing humans to devolve into blood-thirsty rat creatures. Six recently evicted tenants must survive the night and protect their downtown apartment building as the city quickly spirals out of control.

Spiders II: Breeding Ground

Happy couple Jason and Alexandra lose their sail yacht in a storm and are grateful to get picked up by Captain Jim Bigelow's commercial carrier. Suspicious about the ship's doctor and realizing the ship is improbably empty and the radio not broken as the crew claims, Jason starts snooping around. Bodies on meat-hooks, genetic experimentation and giant spiders are what he finds.

Dinocroc

After an African dinosaur ancestor of the crocodile is found, Dr. Campbell uses its DNA to create prototypes at Paula Kennedy's Gereco lab.

Bottom Feeder

A group of utility workers are trapped in a series of tunnels which, unfortunately, contain a scientist mutated by his own creation. The creature feeds instantly on a rat, becoming what it has eaten.

Sharktopus

The U.S. Navy's special group "Blue Water" builds a half-shark, half-octopus for combat. But the sharktopus escapes and terrorizes the beaches of Puerto Vallarta.

Black Swarm

A widow, Deputy Sheriff Jane Kozik, moves from Manhattan to Black Stone, New York, with her daughter Kelsey. There she expects to find a safe place to live. The day after moving, a homeless man is found dead in the tool shed of Jane's blind friend Beverly; an entomologist, Katherine is summoned to help with the investigation, along with Devin, Jane's brother-in-law and former boyfriend. Meanwhile, Kelsey befriends Eli, a scientist who has developed genetically modified wasps to the army as a weapon, and who is now trying to revert the process. When the wasps attack Black Stone, Jane, Devin and Eli team-up to attempt to destroy the swarm.

In the Spider's Web

When a team of backpackers sets out to explore the Indian jungles, one of them is bitten by a poisonous spider and killed.

Shark Night 3D

A weekend at a lake house in the Louisiana Gulf turns into a nightmare for seven vacationers as they are subjected to fresh-water shark attacks.

Piranhaconda

A hybrid creature - half piranha and half anaconda -- attacks a low-budget horror movie crew on location near her nest when her egg is stolen. Now they must outrun and kill the deadly piranhaconda as well as stop the mad scientist who stole the egg - before they all become dinner.

Sharktopus vs. Whalewolf

When a mad scientist mixes the genes of a killer whale and a wolf, it creates the Whalewolf, and it's up to Sharktopus to stop it.

Dinoshark

A baby dinoshark evolves into a ferocious predatory adult, terrorising tourists and locals offshore from Puerto Vallarta, Mexico.

suggested by: ShadowyScallop

Infested

Horror tale of insects which eat their victims from the inside out.

Spring Break Shark Attack

A young teenager travels to Florida, unknowing that a group of dangerous tiger sharks are ravaging the beach.

Snakehead Swamp

A horrifying hybrid of genetic science and nature has taken over the Louisiana bayou, leaving terror in its wake! In the heat of the summer, what began as an day of boating and bikinis changes drastically when a school of genetically enhanced snakehead fish finds their way into Black Briar Swamp.

Fangs

Scottsville is a sleepy town, where the yearly apple blossom festival is usually the only 'memorable' event, so Police Chief Sam Taylor is furious when young cop Ally Parks -who comes from the big city- insists on investigating the death and mutilation of prof. Fuller, who experimented on bats, and soon several other victims, as unnatural bat attacks. She finds a helpful 'expert' in animal controller Dr. John Winslow, and the couple gets help from his inquisitive daughter Genny and her practically in-living high school-friend Logan to unravel how it all ties in with local real estate mogul Carl Hart's dishonest and corrupt practices.

Spiders

A DNA experiment on a rare breed of spider is taking place on a NASA space shuttle, when a freak meteor shower engulfs the shuttle, causing everything to go horribly wrong. One survivor is found on the ship and watched over in a secret location deep in the California desert. The problem continues, as the survivor isn't alone, as another deadly spiders climbs out of him and goes on a rampage around the ship. Curious reporter Marci Eyre must now survive, escape and warn everyone before the spider reaches outside the desert.

suggested by: user364yw7ox6f7

They Crawl

A computer whiz named 'Bean' is among several people found dead with strange striations, odd puncture wounds and missing internal organs. Bean's brother Ted teams up with detective Gina to get to the bottom of it. With the help of a computer hacker, they find a blueprint that reveals the killer who has been terrorizing the city...a rampaging posse of genetically mutated cockroaches!

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